Ringed Plaque Formation in Infectious Pancreatic Necrosis Virus Correlates with Defective Interfering Particle Production
نویسندگان
چکیده
منابع مشابه
DNA immunization and viral load in vaccinated trout following experimental infection with infectious pancreatic necrosis virus (IPNV)
متن کامل
Biophysical studies of infectious pancreatic necrosis virus.
The molecular weight of infectious pancreatic necrosis virus (IPNV) has been determined by analytical ultracentrifugation and dynamic light scattering. The sedimentation coefficient of the virus was found to be 435S. The average value for molecular weight is (55 +/- 7) x 106. The virus genome consists of two segments of double-stranded RNA (molecular weights, 2.5 x 106 and 2.3 x 106), which rep...
متن کاملIsolation and expression of recombinant viral protein (VP2) from Iranian isolates of Infectious Pancreatic Necrosis Virus (IPNV) in Escherichia coli
Infectious Pancreatic Necrosis Virus (IPNV) is a member of the family Birnaviridae that has been linked to high mortalities in salmonids. Bacterial based systems as live vectors for the delivery of heterologous antigens offer a number of advantages as vaccination strategies. VP2 is a structural viral protein of IPNV with immunogenicity effects. In this study IPNV was isolated from diseased fry ...
متن کاملInfectious Pancreatic Necrosis
Infectious pancreatic necrosis (IPN) is a viral infection primarily of trout and salmon, but the virus has also been isolated from a wide variety of other fish species. The infection is characteristically seen in trout as an acute disease causing high mortality in fry and fingerlings. However, it may also occur as a benign and inconspicuous infection (Bullock et al. 1976). Because high fish los...
متن کاملReplication of vesicular stomatitis virus defective interfering particle RNA in vitro: transition from synthesis of defective interfering leader RNA to synthesis of full-length defective interfering RNA.
The replication of the RNA of vesicular stomatitis virus (VSV) defective interfering (DI) particles was established in a defined cell-free system. The transition from synthesis of only the DI-leader RNA to replication of the full-length DI RNA was effected in the system by newly synthesized VSV proteins and occurred in the absence of VSV helper virus. Both positive- and negative-polarity full-l...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 1978
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-41-3-623